Guillain Barre Syndrome

Wednesday, September 12, 2012

GBS (Guillain Barre Syndrome) is a heterogeneous group of immune-mediated process, a rare disorder, wherein the immune system attacks the nerves themselves. The disorder is characterized by motor dysfunction, sensory, and autonomic. From its classical form, GBS is a demyelinating polineuopati with characteristic muscle weakness and progressive symmetrical ascending paralysis, and hiporefleksi, with or without sensory or autonomic symptoms. However, there is a variant of GBS involving cranial nerves or pure motor. In severe cases, the muscle weakness that can lead to life-threatening respiratory failure.

Causes of Guillain Barre Syndrome

The exact cause of the disease is unknown, but it is generally triggered by a respiratory or gastrointestinal infection. All age groups can be affected by this disease, but most often occurs in young adults and the elderly. In the most severe type, Guillain-Barre syndrome becomes a medical emergency condition that requires immediate treatment. Approximately 30% of patients requiring the use of breathing aids while.

Treatments for Guillain Barre Syndrome

The Best treatment for GBS is immunoglobulin administration. The dose is 2 g / kg body weight, the speed of the infusion rate of less than 200 ml / hour. The purpose of giving this drug is a blood plasma center neutralize nerve damage. "With the right dose is injected into the blood vessels, the destroyer antibody gene is expected to be neutral again. However noteworthy, in about 20% of patients, these drugs cause side effects such as muscle aches and chills."

Other therapies are washing the patient plasma (plasmapheresis). Plasma that has been damaged from the patient's body removed and replaced with a new form of liquid plasma albumin 5% salt free for 8-10 days. Plasma is able to shield the body from the damaging autoimmune nerve sac earlier.

While motor disorders experienced by patients undergoing GBS require physiotherapy should start from the beginning, ie since the patient's condition is stable and can undergo instruction from a physiotherapist. It's just that there are two things to note. First, the phase when the symptoms continued while the patient's condition has not seen improvement. In this phase, which is necessary to maintain the condition of the patient, although the patient's condition will continue to decline. Second, the healing phase, ie when the patient's condition improves. In this phase of physiotherapy treatment aimed at strengthening and optimizing the patient's condition.